Chemerin Impact on Alternative mRNA Transcription in the Porcine Luteal Cells.

ABSTRACT: Chemerin participates in the regulation of processes related to physiological and disorder mechanisms in mammals, including metabolism, obesity, inflammation, and reproduction. In this study, we have investigated chemerin influence on alternative mRNA transcription within the porcine luteal cell transcriptome, such as differential expression of long non-coding RNAs (DELs) and their interactions with differentially expressed genes (DEGs), differences in alternative splicing of transcripts (DASs), and allele-specific expression (ASEs) related to the single nucleotide variants (SNVs) frequency. Luteal cells were collected from gilts during the mid-luteal phase of the oestrous cycle. After in vitro culture of cells un-/treated with chemerin, the total RNA was isolated and sequenced using the h

SUBMITTER: Makowczenko KG 

PROVIDER: S-EPMC8870241 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature