Treatment of Malignant Adnexal Tumors of the Skin: A 12-Year Perspective.

ABSTRACT: Malignant adnexal cancers of the skin-extremely rare neoplasms-are mostly reported as non-symptomatic, slow-growing nodules. These carcinomas occur mainly in the middle-aged (50-60 years of age); they are mostly localized on the upper part of the body and are locally aggressive, infiltrate surrounding tissue, and metastasize to regional lymph nodes. The patients' outcomes depend on multiple prognostic factors, including the size of the primary tumor and its mitotic count. Surgical resection of the primary tumor with or without regional lymph nodes is the treatment method of choice; however, due to aggressive tumor behavior, perioperative treatment may be considered. The role and efficacy of radiotherapy in the treatment of skin adnexal malignancies are not yet fully defined. Some authors s

SUBMITTER: Kleibert M 

PROVIDER: S-EPMC8870474 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature