Persistence of SARS-CoV-2 total immunoglobulins in a series of convalescent plasma and blood donors.

ABSTRACT:

Background

The vast majority of COVID-19 cases both symptomatic and asymptomatic develop immunity after COVID-19 contagion. Whether lasting differences exist between infection and vaccination boosted immunity is yet to be known. The aim of this study was to determine how long total anti-SARS-CoV2 antibodies due to past infection persist in peripheral blood and whether sex, age or haematological features can influence their lasting.

Material and methods

A series of 2421 donations either of SARS-CoV-2 convalescent plasma or whole blood from 1107 repeat donors from January 2020 to March 2021 was analysed. An automated chemiluminescence immunoassay for total antibodies recognizing the nucleocapsid protein of SARS-CoV-2 in human serum and plasma was performed. Sex, age, blood gro

SUBMITTER: Martin MC 

PROVIDER: S-EPMC8870513 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature