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Variation in the COVID-19 infection-fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis.


ABSTRACT:

SUBMITTER: COVID-19 Forecasting Team 

PROVIDER: S-EPMC8871594 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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Variation in the COVID-19 infection-fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis.

Lancet (London, England) 20220224 10334


<h4>Background</h4>The infection-fatality ratio (IFR) is a metric that quantifies the likelihood of an individual dying once infected with a pathogen. Understanding the determinants of IFR variation for COVID-19, the disease caused by the SARS-CoV-2 virus, has direct implications for mitigation efforts with respect to clinical practice, non-pharmaceutical interventions, and the prioritisation of risk groups for targeted vaccine delivery. The IFR is also a crucial parameter in COVID-19 dynamic tr  ...[more]

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