Ontology highlight
ABSTRACT:
SUBMITTER: Carini G
PROVIDER: S-EPMC8872439 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Carini Giulia G Mingardi Jessica J Bolzetta Francesco F Cester Alberto A Bolner Andrea A Nordera Giampietro G La Via Luca L Ieraci Alessandro A Russo Isabella I Maggi Stefania S Calza Stefano S Popoli Maurizio M Veronese Nicola N Musazzi Laura L Barbon Alessandro A
Genes 20220126 2
Frailty is an aging-related pathology, defined as a state of increased vulnerability to stressors, leading to a limited capacity to meet homeostatic demands. Extracellular microRNAs (miRNAs) were proposed as potential biomarkers of various disease conditions, including age-related pathologies. The primary objective of this study was to identify blood miRNAs that could serve as potential biomarkers and candidate mechanisms of frailty. Using the Fried index, we enrolled 22 robust and 19 frail subj ...[more]