High Stability of the Epigenome in Drosophila Interspecific Hybrids.

ABSTRACT: Interspecific hybridization is often seen as a genomic stress that may lead to new gene expression patterns and deregulation of transposable elements (TEs). The understanding of expression changes in hybrids compared with parental species is essential to disentangle their putative role in speciation processes. However, to date we ignore the detailed mechanisms involved in genomic deregulation in hybrids. We studied the ovarian transcriptome and epigenome of the Drosophila buzzatii and Drosophila koepferae species together with their F1 hybrid females. We found a trend toward underexpression of genes and TE families in hybrids. The epigenome in hybrids was highly similar to the parental epigenomes and showed intermediate histone enrichments between parental species in most cases. Differenti

SUBMITTER: Bodelon A 

PROVIDER: S-EPMC8872975 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature