Determinants of cord blood adipokines and association with neonatal abdominal adipose tissue distribution.

ABSTRACT:

Background

Cord blood leptin and adiponectin are adipokines known to be associated with birth weight and overall infant adiposity. However, few studies have investigated their associations with abdominal adiposity in neonates. We examined maternal factors associated with cord blood leptin and adiponectin, and the association of these adipokines with neonatal adiposity and abdominal fat distribution measured by magnetic resonance imaging (MRI) in an Asian mother-offspring cohort.

Methods

Growing Up in Singapore Towards healthy Outcomes (GUSTO), is a prospective mother-offspring birth cohort study in Singapore. Cord blood plasma leptin and adiponectin concentrations were measured using Luminex and Enzyme-Linked Immunosorbent Assay respectively in 816 infants. A total of 271 ne

SUBMITTER: Tan K 

PROVIDER: S-EPMC8873009 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature