Quantitative myocardial perfusion response to adenosine and regadenoson in patients with suspected coronary artery disease.

ABSTRACT:

Background

The aim of the present study was to compare the quantitative flow responses of regadenoson against adenosine using cardiac ¹⁵O-water PET imaging in patients with suspected or known coronary artery disease (CAD).

Methods

Hyperemic myocardial blood flow (MBF) after adenosine and regadenoson was compared using correlation and Bland-Altman analysis in 21 patients who underwent rest and adenosine ¹⁵O-water PET scans followed by rest and regadenoson ¹⁵O-water PET scans.

Results

Global mean (± SD) MBF values at rest and stress were 0.92 ± 0.27 and 2.68 ± 0.80 mL·g·min for the adenosine study and 0.95 ± 0.29 and 2.76 ± 0.79 mL·g·min for the regadenoson study (P = 0.55 and P = 0.49). The correlations between global and regional adeno

SUBMITTER: Kero T 

PROVIDER: S-EPMC8873130 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature