New Insights and Emerging Therapeutic Approaches in Prostate Cancer.

ABSTRACT: Prostate cancer is the second most frequently diagnosed cancer in men and several therapeutic approaches are currently available for patient's care. Although the androgen receptor status represents a good predictor of response to androgen deprivation therapy, prostate cancer frequently becomes resistant to this approach and spreads. The molecular mechanisms that contribute to progression and drug-resistance of this cancer remain still debated. However, few therapeutic options are available for patient's management, at this stage. Recent years have seen a great expansion of the studies concerning the role of stromal-epithelial interactions and tumor microenvironment in prostate cancer progression. The findings so far collected have provided new insights into diagnostic and clinical manageme

SUBMITTER: Licitra F 

PROVIDER: S-EPMC8873523 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature