Genomic surveillance of Acinetobacter baumannii in the Philippines, 2013-2014.

ABSTRACT:

Objective

Acinetobacter baumannii is an opportunistic nosocomial pathogen that has increasingly become resistant to carbapenems worldwide. In the Philippines, rates of carbapenem resistance and multidrug resistance are above 50%. We undertook a genomic study of carbapenem-resistant A. baumannii in the Philippines to characterize the population diversity and antimicrobial resistance mechanisms.

Methods

We sequenced the whole genomes of 117 A. baumannii isolates recovered by 16 hospitals in the Philippines between 2013 and 2014. From the genome sequences, we determined the multilocus sequence type, presence of acquired determinants of antimicrobial resistance and relatedness between isolates. We also compared the phenotypic and genotypic resistance results

SUBMITTER: Chilam J 

PROVIDER: S-EPMC8873916 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature