Feasibility of a tailored home-based exercise intervention during neoadjuvant chemotherapy in breast cancer patients.

ABSTRACT:

Purpose

To evaluate the feasibility of a home-based moderate-to-vigorous intensity, phased (introduction, intermediate, maintenance), exercise prescription in breast cancer patients receiving cardiotoxic neoadjuvant chemotherapy.

Methods

Nineteen breast cancer patients were randomized to intervention or control for the duration of chemotherapy (16-24 weeks). The intervention was one aerobic exercise session at 80-90% VO_2max for 25 min/week and 65%-75% VO_2max for ≥ 50 min/week. Adherence to the tailored home-based program was assessed by heart rate monitors. Acceptability, tolerability, feasibility, efficacy, change in VO_2max, and patient reported outcomes, safety, and clinical events were assessed.

Results

25.7% of eligible women conse

SUBMITTER: Sturgeon KM 

PROVIDER: S-EPMC8874298 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature