A New Meal Absorption Model for Artificial Pancreas Systems.

ABSTRACT:

Background

Artificial pancreas (AP) systems reduce the treatment burden of Type 1 Diabetes by automatically regulating blood glucose (BG) levels. While many disturbances stand in the way of fully closed-loop (automated) control, unannounced meals remain the greatest challenge. Furthermore, different types of meals can have significantly different glucose responses, further increasing the uncertainty surrounding the meal.

Methods

Effective attenuation of a meal requires quick and accurate insulin delivery because of slow insulin action relative to meal effects on BG. The proposed Variable Hump (VH) model adapts to meals of varying compositions by inferring both meal size and shape. To appropriately address the uncertainty of meal size, the model divides meal abs

SUBMITTER: Diamond T 

PROVIDER: S-EPMC8875069 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature