Study for Evaluation of Hydrogels after the Incorporation of Liposomes Embedded with Caffeic Acid.

ABSTRACT: Caffeic acid (CA), a phenolic acid, is a powerful antioxidant with proven effectiveness. CA instability gives it limited use, so encapsulation in polymeric nanomaterials has been used to solve the problem but also to obtain topical hydrogel formulas. Two different formulas of caffeic acid liposomes were incorporated into three different formulas of carbopol-based hydrogels. A Franz diffusion cell system was used to evaluate the release of CA from hydrogels. For the viscoelastic measurements of the hydrogels, the equilibrium flow test was used. The dynamic tests were examined at rest by three oscillating tests: the amplitude test, the frequency test and the flow and recovery test. These carbopol gels have a high elasticity at flow stress even at very low polymer concentrations. In the analy

SUBMITTER: Dejeu IL 

PROVIDER: S-EPMC8875116 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature