Predictors of Left Main Coronary Artery Disease in the ISCHEMIA Trial.

ABSTRACT:

Background

Detection of ≥50% diameter stenosis left main coronary artery disease (LMD) has prognostic and therapeutic implications. Noninvasive stress imaging or an exercise tolerance test (ETT) are the most common methods to detect obstructive coronary artery disease, though stress test markers of LMD remain ill-defined.

Objectives

The authors sought to identify markers of LMD as detected on coronary computed tomography angiography (CTA), using clinical and stress testing parameters.

Methods

This was a post hoc analysis of ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches), including randomized and nonrandomized participants who had locally determined moderate or severe ischemia on nonimaging ETT, stress nuclear my

SUBMITTER: Senior R 

PROVIDER: S-EPMC8875308 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature