Ontology highlight
ABSTRACT:
SUBMITTER: Escobar M
PROVIDER: S-EPMC8875492 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Escobar Miguel M Mancuso Maria Elisa ME Hermans Cedric C Leissinger Cindy C Seifert Wilfried W Li Yanyan Y McKeand William W Oldenburg Johannes J
Journal of clinical medicine 20220218 4
Hemophilia B is a bleeding disorder caused by a deficiency of coagulation factor IX (FIX). Treatment with FIX replacement products can increase FIX activity levels to minimize or prevent bleeding events. However, frequent dosing with standard-acting FIX products can create a high treatment burden. Long-acting products have been developed to maintain bleed protection with extended dosing intervals. Recombinant factor IX-albumin fusion protein (rIX-FP) is a long-acting product indicated for the tr ...[more]