Formation of Aggregate-Free Gold Nanoparticles in the Cyclodextrin-Tetrachloroaurate System Follows Finke-Watzky Kinetics.

ABSTRACT: Cyclodextrin-capped gold nanoparticles are promising drug-delivery vehicles, but the technique of their preparation without trace amounts of aggregates is still lacking, and the size-manipulation possibility is very limited. In the present study, gold nanoparticles were synthesized by means of 0.1% (w/w) tetrachloroauric acid reduction with cyclodextrins at room temperature, at cyclodextrin concentrations of 0.001 M, 0.002 M and 0.004 M, and pH values of 11, 11.5 and 12. The synthesized nanoparticles were characterized by dynamic light scattering in both back-scattering and forward-scattering modes, spectrophotometry, X-ray photoelectron spectroscopy, transmission electron microscopy and Fourier-transform infrared spectroscopy. These techniques revealed 14.9% Au1+ on their surfaces. The Fi

SUBMITTER: Pestovsky YS 

PROVIDER: S-EPMC8875903 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature