Gut microbiota in pregnant Malaysian women: a comparison between trimesters, body mass index and gestational diabetes status.

ABSTRACT:

Background

The primary purpose of the study is to determine the variation of gut microbiota composition between first (T1) and third trimester (T3); gestational diabetes mellitus (GDM) and non-gestational diabetes mellitus (NGDM); and also within a different category of Body Mass Index (BMI) of selected pregnant Malaysian women.

Methods

A prospective observational study on selected 38 pregnant Malaysian women attending a tertiary medical centre was carried out. Those with preexisting diabetes, metabolic syndrome or any other endocrine disorders were excluded. GDM was determined using oral glucose tolerance test (OGTT) while BMI was stratified as underweight, normal, pre-obese and obese. Fecal samples were then collected during the first trimester (T1) and the third trimester

SUBMITTER: Abdullah B 

PROVIDER: S-EPMC8876553 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature