Long-term follow-up of dynamic brain changes in patients recovered from COVID-19 without neurological manifestations.

ABSTRACT: BACKGROUNDAfter the initial surge in COVID-19 cases, large numbers of patients were discharged from a hospital without assessment of recovery. Now, an increasing number of patients report postacute neurological sequelae, known as "long COVID" - even those without specific neurological manifestations in the acute phase.METHODSDynamic brain changes are crucial for a better understanding and early prevention of "long COVID." Here, we explored the cross-sectional and longitudinal consequences of COVID-19 on the brain in 34 discharged patients without neurological manifestations. Gray matter morphology, cerebral blood flow (CBF), and volumes of white matter tracts were investigated using advanced magnetic resonance imaging techniques to explore dynamic brain changes from 3 to 10 months after di

SUBMITTER: Tian T 

PROVIDER: S-EPMC8876627 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature