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Age-Related Changes in Lipid and Glucose Levels Associated with Drug Use and Mortality: An Observational Study.


ABSTRACT: The pathogenesis of type 2 diabetes mellitus is complex and still unclear in some details. The main feature of diabetes mellitus is high serum glucose, and the question arises of whether there are other statistically observable dysregulations in laboratory measurements before the state of hyperglycemia becomes severe. In the present study, we aim to examine glucose and lipid profiles in the context of age, sex, medication use, and mortality. We conducted an observational study by analyzing laboratory data from 506,083 anonymized laboratory tests from 63,606 different patients performed by a regional laboratory in Slovenia between 2008 and 2019. Laboratory data-based results were evaluated in the context of medication use and mortality. The medication use database contains anonymized record

SUBMITTER: Markovic R 

PROVIDER: S-EPMC8876997 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature