Academ Virus, a Novel Hantavirus in the Siberian Mole (Talpa altaica) from Russia.

ABSTRACT: To date, six hantavirus species have been detected in moles (family Talpidae). In this report, we describe Academ virus (ACDV), a novel hantavirus harbored by the Siberian mole (Talpa altaica) in Western Siberia. Genetic analysis of the complete S-, M-, and partial L-genomic segments showed that ACDV shared a common evolutionary origin with Bruges virus, previously identified in the European mole (Talpa europaea), and is distantly related to other mole-borne hantaviruses. Co-evolution and local adaptation of genetic variants of hantaviruses and their hosts, with possible reassortment events, might have shaped the evolutionary history of ACDV.

SUBMITTER: Yashina LN 

PROVIDER: S-EPMC8877406 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature