Phi 6 Bacteriophage Inactivation by Metal Salts, Metal Powders, and Metal Surfaces.

ABSTRACT: The interaction of phages with abiotic environmental surfaces is usually an understudied field of phage ecology. In this study, we investigated the virucidal potential of different metal salts, metal and ceramic powders doped with Ag and Cu ions, and newly fabricated ceramic and metal surfaces against Phi6 bacteriophage. The new materials were fabricated by spark plasma sintering (SPS) and/or selective laser melting (SLM) techniques and had different surface free energies and infiltration features. We show that inactivation of Phi6 in solutions with Ag and Cu ions can be as effective as inactivation by pH, temperature, or UV. Adding powder to Ag and Cu ion solutions decreased their virucidal effect. The newly fabricated ceramic and metal surfaces showed very good virucidal activity. In par

SUBMITTER: Molan K 

PROVIDER: S-EPMC8877498 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature