Phylogenetic, Functional and Safety Features of 1950s B. infantis Strains.

ABSTRACT: Strains of Bifidobacterium longum subsp. infantis (B. infantis) are amongst the first to colonize the infant gut, partly due to their capacity to metabolize complex human milk oligosaccharides (HMO), and are proposed to play a key role in the development of the infant gut. Since early life, B. infantis supplementation is of high interest, and detailed phylogenetic, functional and safety characterization of the selected strains should be pursued. Using a combination of long and short-read sequencing technologies, we first decipher the genetic distance between different isolates of the same B. infantis strain. Using the same approach, we show that several publicly available genomes recapitulate this strain-level distance as compared to two of the first stra

SUBMITTER: Duboux S 

PROVIDER: S-EPMC8879182 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature