The Hitchhiker's Guide to Human Therapeutic Nanoparticle Development.

ABSTRACT: Nanomedicine plays an essential role in developing new therapies through novel drug delivery systems, diagnostic and imaging systems, vaccine development, antibacterial tools, and high-throughput screening. One of the most promising drug delivery systems are nanoparticles, which can be designed with various compositions, sizes, shapes, and surface modifications. These nanosystems have improved therapeutic profiles, increased bioavailability, and reduced the toxicity of the product they carry. However, the clinical translation of nanomedicines requires a thorough understanding of their properties to avoid problems with the most questioned aspect of nanosystems: safety. The particular physicochemical properties of nano-drugs lead to the need for additional safety, quality, and efficacy testi

SUBMITTER: Ramos TI 

PROVIDER: S-EPMC8879439 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature