The relationship between congenital heart disease and cancer in Swedish children: A population-based cohort study.

ABSTRACT:

Background

Birth defects have been consistently associated with elevated childhood cancer risks; however, the relationship between congenital heart disease (CHD) and childhood cancer remains conflicting. Considering the increasing patient population with CHD after improvements in their life expectancies, insights into this relationship are particularly compelling. Thus, we aimed to determine the relationship between CHD and cancer in Swedish children.

Methods and findings

All individuals registered in the Swedish Medical Birth Register (MBR) between 1973 and 2014 were included in this population-based cohort study (n = 4,178,722). Individuals with CHD (n = 66,892) were identified from the MBR and National Patient Register, whereas cancer diagnoses were retrieved from the Swe

SUBMITTER: Kampitsi CE 

PROVIDER: S-EPMC8880823 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature