A multistate model of health transitions in older people: a secondary analysis of ASPREE clinical trial data.

ABSTRACT:

Background

Understanding the nature of transitions from a healthy state to chronic diseases and death is important for planning health-care system requirements and interventions. We aimed to quantify the trajectories of disease and disability in a population of healthy older people.

Methods

We conducted a secondary analysis of data from the ASPREE trial, which was done in 50 sites in Australia and the USA and recruited community-dwelling, healthy individuals who were aged 70 years or older (≥65 years for Black and Hispanic people in the USA) between March 10, 2010, and Dec 24, 2014. Participants were followed up with annual face-to-face visits, biennial assessments of cognitive function, and biannual visits for physical function until death or June 12, 2017, whichever occurr

SUBMITTER: Neumann JT 

PROVIDER: S-EPMC8880962 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature