Ontology highlight
ABSTRACT:
SUBMITTER: Jing SX
PROVIDER: S-EPMC8881394 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Jing Shu-Xi SX Alania Yvette Y Reis Mariana M McAlpine James B JB Chen Shao-Nong SN Bedran-Russo Ana K AK Pauli Guido F GF
Journal of natural products 20220202 2
To enable the further exploration of structure-activity relationships (SARs) of proanthocyanidins (PACs) with dentin biomodification abilities, <i>Cinnamomum verum</i> was selected for scaled-up purification of mixed A-/B-type, medium-size PAC oligomers. Sequential purification by centrifugal partition chromatography (CPC), Sephadex LH-20, and semiprep HPLC chromatography yielded four underivatized tetrameric (<b>5</b>-<b>8</b>) and two pentameric (<b>9</b>-<b>10</b>) PACs. Their unambiguous str ...[more]