Cost-effectiveness of sleeping sickness elimination campaigns in five settings of the Democratic Republic of Congo.

ABSTRACT: Gambiense human African trypanosomiasis (gHAT) is marked for elimination of transmission by 2030, but the disease persists in several low-income countries. We couple transmission and health outcomes models to examine the cost-effectiveness of four gHAT elimination strategies in five settings - spanning low- to high-risk - of the Democratic Republic of Congo. Alongside passive screening in fixed health facilities, the strategies include active screening at average or intensified coverage levels, alone or with vector control with a scale-back algorithm when no cases are reported for three consecutive years. In high or moderate-risk settings, costs of gHAT strategies are primarily driven by active screening and, if used, vector control. Due to the cessation of active screening and vector cont

SUBMITTER: Antillon M 

PROVIDER: S-EPMC8881616 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature