Neural Changes in Reward Processing Following Approach Avoidance Training for Depression.

ABSTRACT: Altered approach motivation is hypothesized to be critical for the maintenance of depression. Computer-administered approach-avoidance training programs to increase approach action tendencies toward positive stimuli produce beneficial outcomes. However, there have been few studies examining neural changes following approach-avoidance training. Participants with Major Depressive Disorder were randomized to an Approach Avoidance Training (AAT) manipulation intended to increase approach tendencies for positive social cues (n=13) or a control procedure (n=15). We examined changes in neural activation (primary outcome) and connectivity patterns using Group Iterative Multiple Model Estimation during a social reward anticipation task (exploratory). A laboratory-based social affiliation task was a

SUBMITTER: Bomyea J 

PROVIDER: S-EPMC8881638 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature