Drug-induced interstitial lung disease during cancer therapies: expert opinion on diagnosis and treatment.

ABSTRACT:

Background

Drug-induced interstitial lung disease (DIILD) is a form of interstitial lung disease resulting from exposure to drugs causing inflammation and possibly interstitial fibrosis. Antineoplastic drugs are the primary cause of DIILD, accounting for 23%-51% of cases, with bleomycin, everolimus, erlotinib, trastuzumab-deruxtecan and immune checkpoint inhibitors being the most common causative agents. DIILD can be difficult to identify and manage, and there are currently no specific guidelines on the diagnosis and treatment of DIILD caused by anticancer drugs.

Objective

To develop recommendations for the diagnosis and management of DIILD in cancer patients.

Methods

Based on the published literature and their clinical expertise, a multidisciplinary group of experts

SUBMITTER: Conte P 

PROVIDER: S-EPMC8881716 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature