Longitudinal 5-year prediction of cognitive impairment among men with HIV disease.

ABSTRACT:

Background

Although combination antiretroviral therapy reduced the prevalence of HIV-associated dementia, milder syndromes persist. Our goals were to predict cognitive impairment of the Multicenter AIDS Cohort Study (MACS) participants 5 years ahead and from a large pool of factors, select the ones that mostly contributed to our predictions.

Design

Longitudinal, natural and treated history of HIV infection among MSM.

Methods

The MACS is a longitudinal study of the natural and treated history of HIV disease in MSM; the neuropsychological substudy aims to characterize cognitive disorders in men with HIV disease.

Results

We modeled on an annual basis the risk of cognitive impairment 5 years in the future. We were able to predict cognitive impairment at individual

SUBMITTER: Oliveira NL 

PROVIDER: S-EPMC8881797 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature