Grey matter covariation and the role of emotion reappraisal in mental wellbeing and resilience after early life stress exposure.

ABSTRACT: Resilience is a process of adaptive recovery crucial in maintaining mental wellbeing after stress exposure. A psychological factor known to buffer stress and promote positive wellbeing outcomes is the ability to regulate emotions. However, the neural networks underlying resilience, and the possible mediating role of emotion regulation, remain largely unknown. Here, we examined the association between resilience and grey matter covariation (GMC) in healthy adults with and without early life stress (ELS) exposure, and whether emotion regulation mediated this brain-resilience association. Source-based morphometry was used to identify spatial patterns of common GMC in 242 healthy participants. Wellbeing was measured using the COMPAS-W Wellbeing Scale. Linear mixed models were run to establish

SUBMITTER: Park HRP 

PROVIDER: S-EPMC8882193 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature