Weight Gain After Smoking Cessation and Cancer Risk in 3 Prospective Cohorts in the United States.

ABSTRACT:

Background

It remains unknown how cancer risks vary by duration of smoking cessation and whether the benefit is attenuated by postcessation weight gain.

Methods

We prospectively followed 198 565 persons from the Nurses' Health Study (1978-2016), Nurses' Health Study II (1991-2017), and Health Professionals Follow-up Study (1988-2016) who were free of cancer at baseline. We used proportional hazard Cox models to compare cancer risk between current smokers and former smokers with different durations of smoking cessation and postcessation weight gains.

Results

During 4 718 199 person-years of follow-up, we identified 32 456 cases of total cancer. Compared with current smokers, the risks for total and smoking-related cancer in past smokers were reduced to the level simila

SUBMITTER: Hu Y 

PROVIDER: S-EPMC8882388 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature