A comprehensive analysis of renal cell carcinoma as first and second primary cancers.

ABSTRACT:

Objective

Second primary renal cell carcinoma (2nd RCC) refers to renal cell carcinoma (RCC) diagnosed after another unrelated malignancy. This study aims to compare the clinical manifestation, pathology, treatment, and prognostic features of patients with 2nd RCC and first primary renal cell carcinoma (1st RCC).

Materials and methods

Data of the patients with localized RCC were retrospectively collected. They were classified as 2nd RCC or 1st RCC according to a previously diagnosed cancer, including 113 cases of 2nd RCC and 749 cases of 1st RCC.

Results

The most common types of extrarenal malignancies in patients with 2nd RCC include lung, colorectal, breast, gynecological, and gastric cancers. The age and smoking rate of 2nd RCC patients were significantly higher th

SUBMITTER: Chen J 

PROVIDER: S-EPMC8883617 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature