Virtual injections using 4D flow MRI with displacement corrections and constrained probabilistic streamlines.

ABSTRACT:

Purpose

Streamlines from 4D-flow MRI have been used clinically for intracranial blood-flow tracking. However, deterministic and stochastic errors degrade streamline quality. The purpose of this study is to integrate displacement corrections, probabilistic streamlines, and novel fluid constraints to improve selective blood-flow tracking and emulate "virtual bolus injections."

Methods

Both displacement artifacts (deterministic) and velocity noise (stochastic) inherently occur during phase-contrast MRI acquisitions. Here, two displacement correction methods, single-step and iterative, were tested in silico with simulated displacements and were compared with ground-truth velocity fields. Next, the effects of combining displacement corrections and constrained probabilistic stream

SUBMITTER: Roberts GS 

PROVIDER: S-EPMC8884720 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature