Core-shell nanocomposite of flower-like molybdenum disulfide nanospheres and molecularly imprinted polymers for electrochemical detection of anti COVID-19 drug favipiravir in biological samples.

ABSTRACT: A novel electrochemical sensor is reported for the detection of the antiviral drug favipiravir based on the core-shell nanocomposite of flower-like molybdenum disulfide (MoS₂) nanospheres and molecularly imprinted polymers (MIPs). The MoS₂@MIP core-shell nanocomposite was prepared via the electrodeposition of a MIP layer on the MoS₂ modified electrode, using o-phenylenediamine as the monomer and favipiravir as the template. The selective binding of target favipiravir at the MoS₂@MIP core-shell nanocomposite produced a redox signal in a concentration dependent manner, which was used for the quantitative analysis. The preparation process of the MoS₂@MIP core-shell nanocomposite was optimized. Under the optimal conditions, the sensor exhi

SUBMITTER: Wang S 

PROVIDER: S-EPMC8885316 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature