Hemodynamic variations in arterial wave reflection associated with the application of increasing levels of PEEP in healthy subjects.

ABSTRACT: Positive end-expiratory pressure (PEEP) may affect arterial wave propagation and reflection, thus influencing ventricular loading conditions. The aim of the study was to investigate the hemodynamic variations in arterial wave reflection (i.e., wave reflection time, augmentation index, left ventricular ejection time, diastolic time, SEVR) associated with the application of increasing levels of PEEP in healthy subjects. We conducted a prospective observational study. Study population was selected from students and staff. Pulse contour wave analysis was performed from the right carotid artery during stepwise increase in PEEP levels (from 0 cmH₂O, 5 cmH₂0, 10 cmH₂O) with applanation tonometry. Sixty-two healthy volunteers were recruited. There were no significa

SUBMITTER: Belfiore J 

PROVIDER: S-EPMC8885708 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature