Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study.

ABSTRACT:

Background and purpose

Delirium, an acute reduction in cognitive functioning, hinders stroke recovery and contributes to cognitive decline. Right-hemisphere stroke is linked with higher delirium incidence, likely, due to the prevalence of spatial neglect (SN), a right-brain disorder of spatial processing. This study tested if symptoms of delirium and SN after right-hemisphere stroke are associated with abnormal function of the right-dominant neural networks specialized for maintaining attention, orientation, and arousal.

Methods

Twenty-nine participants with right-hemisphere ischemic stroke undergoing acute rehabilitation completed delirium and SN assessments and functional neuroimaging scans. Whole-brain functional connectivity of 4 right-hemisphere seed regions in the cort

SUBMITTER: Boukrina O 

PROVIDER: S-EPMC8885764 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature