Cardiometabolic profile and leukocyte telomere length in a Black South African population.

ABSTRACT: Several studies have reported a possible association between leucocyte telomere length (LTL) and cardio-metabolic diseases (CMDs). However, studies investigating such association are lacking in South Africa despite having a very high prevalence of CMDs. We investigated the association between LTL and CMD risk profile in a black South African population. This was a cross-sectional study with participants > 21 years of age and residing in five townships in Cape Town. CMD markers were compared between men and women and across quartiles of LTL. Linear and logistic regressions relate increasing quartile and Log₁₀LTL with CMD risk profile, with appropriate adjustment. Among 676-participants, diabetes, obesity and hypertension prevalence were 11.5%, 23.1% and 47.5%. Waist-circumference

SUBMITTER: Ngwa NE 

PROVIDER: S-EPMC8885820 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature