Dysfunction in differential reward-punishment responsiveness in conduct disorder relates to severity of callous-unemotional traits but not irritability.

ABSTRACT:

Background

Conduct disorder (CD) has been associated with dysfunction in reinforcement-based decision-making. Two forms of affective traits that reflect the components of CD severity are callous-unemotional (CU; reduced guilt/empathy) traits and irritability. The form of the reinforcement-based decision-making dysfunction with respect to CD and CU traits remains debated and has not been examined with respect to irritability in cases with CD. The goals of the current study were to determine the extent of dysfunction in differential (reward v. punishment) responsiveness in CD, and CU traits and irritability in participants with CD.

Methods

The study involved 178 adolescents [typically developing (TD; N = 77) and cases with CD (N = 101)]. Participants were

SUBMITTER: Zhang R 

PROVIDER: S-EPMC8885913 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature