The relationship between brain structure and general psychopathology in preadolescents.

ABSTRACT:

Background

An emerging body of literature has indicated that broad, transdiagnostic dimensions of psychopathology are associated with alterations in brain structure across the life span. The current study aimed to investigate the relationship between brain structure and broad dimensions of psychopathology in the critical preadolescent period when psychopathology is emerging.

Methods

This study included baseline data from the Adolescent Brain and Cognitive Development (ABCD) Study^® (n = 11,875; age range = 9-10 years; male = 52.2%). General psychopathology, externalizing, internalizing, and thought disorder dimensions were based on a higher-order model of psychopathology and estimated using Bayesian plausible values. Outcome variables included global and regional c

SUBMITTER: Mewton L 

PROVIDER: S-EPMC8885925 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature