Neurologic Prognostication After Cardiac Arrest Using Brain Biomarkers: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Brain injury biomarkers released into circulation from the injured neurovascular unit are important prognostic tools in patients with cardiac arrest who develop hypoxic ischemic brain injury (HIBI) after return of spontaneous circulation (ROSC).

Objective

To assess the neuroprognostic utility of bloodborne brain injury biomarkers in patients with cardiac arrest with HIBI.

Data sources

Studies in electronic databases from inception to September 15, 2021. These databases included MEDLINE, Embase, Evidence-Based Medicine Reviews, CINAHL, Cochrane Database of Systematic Reviews, and the World Health Organization Global Health Library.

Study selection

Articles included in this systmatic review and meta-analysis were independently assessed by 2 reviewers.

SUBMITTER: Hoiland RL 

PROVIDER: S-EPMC8886448 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature