A Nutrient Formulation Affects Developmental Myelination in Term Infants: A Randomized Clinical Trial.

ABSTRACT:

Background and objectives

Observational studies suggest differences between breast-fed and formula-fed infants in developmental myelination, a key brain process for learning. The study aims to investigate the efficacy of a blend of docosahexaenoic acid (DHA), arachidonic acid (ARA), iron, vitamin B12, folic acid, and sphingomyelin (SM) from a uniquely processed whey protein concentrate enriched in alpha-lactalbumin and phospholipids compared with a control formulation on myelination, cognitive, and behavioral development in the first 6 months of life.

Methods

These are 6-month results from an ongoing two-center, randomized controlled trial with a 12-month intervention period (completed for all participants). In this study, full term, neurotypical infants of both sexes (N<

SUBMITTER: Schneider N 

PROVIDER: S-EPMC8886575 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature