Critical role of rhythms in prefrontal transcranial magnetic stimulation for depression: A randomized sham-controlled study.

ABSTRACT: Repetitive transcranial magnetic stimulation (rTMS) is an alternative treatment for depression, but the neural correlates of the treatment are currently inconclusive, which might be a limit of conventional analytical methods. The present study aimed to investigate the neurophysiological evidence and potential biomarkers for rTMS and intermittent theta burst stimulation (iTBS) treatment. A total of 61 treatment-resistant depression patients were randomly assigned to receive prolonged iTBS (piTBS; N = 19), 10 Hz rTMS (N = 20), or sham stimulation (N = 22). Each participant went through a treatment phase with resting state electroencephalography (EEG) recordings before and after the treatment phase. The aftereffects of stimulation showed that theta-alpha amplitude modulation frequency (f

SUBMITTER: Tsai YC 

PROVIDER: S-EPMC8886663 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature