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Preconception and early-pregnancy risk prediction for birth complications: development of prediction models within a population-based prospective cohort.


ABSTRACT:

Background

Suboptimal maternal health already from preconception onwards is strongly linked to an increased risk of birth complications. To enable identification of women at risk of birth complications, we aimed to develop a prediction model for birth complications using maternal preconception socio-demographic, lifestyle, medical history and early-pregnancy clinical characteristics in a general population.

Methods

In a population-based prospective cohort study among 8340 women, we obtained information on 33 maternal characteristics at study enrolment in early-pregnancy. These characteristics covered the preconception period and first half of pregnancy (< 21 weeks gestation). Preterm birth was < 37 weeks gestation. Small-for-gestational-age (SGA) and large-for-gestational-ag

SUBMITTER: Wahab RJ 

PROVIDER: S-EPMC8886786 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature