The chromatin organization of a chlorarachniophyte nucleomorph genome.

ABSTRACT:

Background

Nucleomorphs are remnants of secondary endosymbiotic events between two eukaryote cells wherein the endosymbiont has retained its eukaryotic nucleus. Nucleomorphs have evolved at least twice independently, in chlorarachniophytes and cryptophytes, yet they have converged on a remarkably similar genomic architecture, characterized by the most extreme compression and miniaturization among all known eukaryotic genomes. Previous computational studies have suggested that nucleomorph chromatin likely exhibits a number of divergent features.

Results

In this work, we provide the first maps of open chromatin, active transcription, and three-dimensional organization for the nucleomorph genome of the chlorarachniophyte Bigelowiella natans. We find that the B. natans nucleomor

SUBMITTER: Marinov GK 

PROVIDER: S-EPMC8887012 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature