Association of Depressive Symptoms with Sleep Disturbance: A Co-twin Control Study.

ABSTRACT:

Background

Few studies have comprehensively evaluated the association of depression with sleep disturbance using a controlled twin study design.

Purpose

To cross-sectionally evaluate the association of depression with both objective and subjective sleep disturbance.

Methods

We studied 246 members of the Vietnam Era Twin Registry. We measured depressive symptoms using the Beck Depression Inventory-II (BDI) and assessed major depression using structured clinical interviews. Twins underwent one-night polysomnography and 7-day actigraphy to derive measures of objective sleep and completed the Pittsburgh Sleep Quality Index for subjective sleep. Multivariable mixed-effects models were used to examine the association.

Results

Twins were all male, mostly white (97%),

SUBMITTER: Huang M 

PROVIDER: S-EPMC8887572 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature