Sense of Purpose in Life Is Associated with Lower Risk of Incident Dementia: A Meta-Analysis.

ABSTRACT:

Background

A sense of purpose in life has been associated with healthier cognitive outcomes across adulthood, including risk of dementia. The robustness and replicability of this association, however, has yet to be evaluated systematically.

Objective

To test whether a greater sense of purpose in life is associated with lower risk of dementia in four population-based cohorts and combined with the published literature.

Methods

Random-effect meta-analysis of prospective studies (individual participant data and from the published literature identified through a systematic review) that examined sense of purpose and risk of incident dementia.

Results

In six samples followed up to 17 years (four primary data and two published; total N = 53,499; n = 5,862 incident deme

SUBMITTER: Sutin AR 

PROVIDER: S-EPMC8887819 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature