Enhanced thread spray mass spectrometry: a general method for direct pesticide analysis in various complex matrices.

ABSTRACT: Determination of pesticide residues in a wide variety of matrices is an ongoing challenge due to low concentration and substantial amounts of interfering endogenous compounds that can be coextracted with the analytes. Herein, we describe the use of cellulose thread both as a suitable sampling medium for various matrices and as a direct analysis platform through an improved thread spray mass spectrometry (MS) approach. Enhanced extraction and the subsequent generation of tiny nanodroplets, after the application of DC potential to the wet thread, enabled ultra-sensitive detection of pesticides without prior sample treatment. This methodology was applied to quantify glyphosate and its metabolite, aminomethylphosphonic acid, in surface water at 12.2 μg mL^-1 limit of detection (LOD)

SUBMITTER: Jackson S 

PROVIDER: S-EPMC8887830 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature