Feedforward and feedback interactions between visual cortical areas use different population activity patterns.

ABSTRACT: Brain function relies on the coordination of activity across multiple, recurrently connected brain areas. For instance, sensory information encoded in early sensory areas is relayed to, and further processed by, higher cortical areas and then fed back. However, the way in which feedforward and feedback signaling interact with one another is incompletely understood. Here we investigate this question by leveraging simultaneous neuronal population recordings in early and midlevel visual areas (V1-V2 and V1-V4). Using a dimensionality reduction approach, we find that population interactions are feedforward-dominated shortly after stimulus onset and feedback-dominated during spontaneous activity. The population activity patterns most correlated across areas were distinct during feedforward- and

SUBMITTER: Semedo JD 

PROVIDER: S-EPMC8888615 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature