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Three-vessel spontaneous coronary artery dissection in a patient with hyperhomocysteinemia.


ABSTRACT: Increased homocysteine has been related to the occurrence of dissections in the coronary circulation, aorta, and cervical arteries. Spontaneous coronary artery dissection (SCAD) is a relatively rare phenomenon, and data on the long-term follow-up of patients with SCAD are extremely limited. Herein, we describe a case of a young male patient with 3-vessel SCAD (presence of radiolucent linear defects indicating the presence of dissections in all three major coronary arteries) who was found to have hyperhomocysteinemia and a concurrent methylenetetrahydrofolate reductase prothrombotic mutation. Despite the presence of multi-vessel SCAD, the patient had clinically stable coronary artery disease for a long period. <Learning objective: Three-vessel spontaneous coronary artery dissection (

SUBMITTER: Katsouras CS 

PROVIDER: S-EPMC8888715 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature